Delete all your gists

index.js

var async = require('async');
var GitHubApi = require('github');

var github = new GitHubApi({
  version: '3.0.0',
  protocol: 'https'
});

github.authenticate({
  type: 'basic',
  username: 'user',
  password: 'pass'
});

async.waterfall([
  function (callback) {
    github.gists.getAll({}, callback);
  },
  function (gists, callback) {
    // filter gists by properties as needed
    async.each(gists, function (gist, callback) {
      github.gists.delete({
        id: gist.id
      }, callback);
    }, callback);
  }
], function (err) {
  if (err) {
    console.log('Execution failed: %s', err.message);
    process.exit(1);
  }
  console.log('Done!');
  process.exit(0);
});