timeline3.json

{ "nodes" : [
{"id":"CHAPERONE","group":2012},
{"id":"LATS-YAP","group":2013},
{"id":"NF3:NF2:NF1","group":2013},
{"id":"YKI/YAP","group":1985},
{"id":"INHIBITION","group":1985},
{"id":"INTERACT","group":2009},
{"id":"REGULATION.NF2","group":1992},
{"id":"SALVADOR/WARTS/HIPPO","group":2001},
{"id":"C-TERMINAL DEFICIENT MERLIN MUTANT","group":2001},
{"id":"DROSOPHILA MERLIN","group":2001},
{"id":"Δ2-4)MERLIN","group":2001},
{"id":"COMPETITIVE","group":2002},
{"id":"IMPAIR","group":2004},
{"id":"SUPPRESS","group":2007},
{"id":"INHIBIT","group":2007},
{"id":"PATIENT-DERIVED MERLIN MUTANTS","group":2007},
{"id":"MERLIN","group":2008},
{"id":"SUPPRESSION.NF2","group":2009},
{"id":"ENHANCE","group":2009},
{"id":"REPRESS","group":2011},
{"id":"MELANOMA),NF2(IE","group":2011},
{"id":"CLEAVAGE","group":2011},
{"id":"ERM/NF2","group":2011},
{"id":"NEUROFIBROMATOSIS 2 (NF2) TUMOR SUPPRESSOR GENE","group":2011},
{"id":"CRL4","group":2012},
{"id":"IMPROVE","group":2012},
{"id":"NON-NF2 POPULATION","group":2013},
{"id":"RESCUE","group":2016},
{"id":"SCHWANNOMIN/MERLIN","group":2016},
{"id":"YAP","group":2016},
{"id":"YAP1","group":1994},
{"id":"NEUROFIBROMATOSIS 2 (NF2) GENE","group":1994},
{"id":"HIPPO","group":1994},
{"id":"OPERATION.NF2","group":1994},
{"id":"CONTROL","group":2000},
{"id":"HIPPO KINASE","group":2000},
{"id":"WTS/LATS","group":2000},
{"id":"COFACTOR","group":2000},
{"id":"LOSS OF FUNCTION","group":2003},
{"id":"DISRUPT","group":2006},
{"id":"TUMOUR SUPPRESSOR MERLIN","group":2006},
{"id":"DOMINANT","group":2010},
{"id":"UBIQUITIN","group":2011},
{"id":"BENEFIT","group":2011},
{"id":"FRAMESHIFT","group":2011},
{"id":"NF2","group":2013},
{"id":"ERBIN/MERLIN","group":2013},
{"id":"SALVADOR-WARTS-HIPPO","group":2013},
{"id":"RECESSIVE","group":2003},
{"id":"HIPPOCAMPAL","group":2003},
{"id":"WARTS/LATS","group":2013},
{"id":"LATS1-PSEN1","group":2013},
{"id":"BIND","group":2013},
{"id":"TUMOR SUPPRESSOR MERLIN","group":2003},
{"id":"INSERT","group":2003},
{"id":"HOUSE-BRACKMANNNF2","group":2003},
{"id":"NON-NF2","group":1998},
{"id":"BLOCK","group":1998}
],
"links": [
{"source":"BIND","target":"NF2","value": 103},
{"source":"BIND","target":"NF3:NF2:NF1","value": 30},
{"source":"NF2","target":"BIND","value": 103},
{"source":"NF2","target":"NF3:NF2:NF1","value": 81},
{"source":"NF3:NF2:NF1","target":"BIND","value": 30},
{"source":"NF3:NF2:NF1","target":"NF2","value": 81},
{"source":"CONTROL","target":"INHIBITION","value": 108},
{"source":"DOMINANT","target":"NF2","value": 107},
{"source":"INHIBITION","target":"CONTROL","value": 108},
{"source":"NF2","target":"DOMINANT","value": 107},
{"source":"NF2","target":"RECESSIVE","value": 89},
{"source":"RECESSIVE","target":"NF2","value": 89},
{"source":"DOMINANT","target":"MERLIN","value": 108},
{"source":"MERLIN","target":"DOMINANT","value": 108},
{"source":"BIND","target":"IMPAIR","value": 42},
{"source":"BIND","target":"INTERACT","value": 62},
{"source":"BIND","target":"MERLIN","value": 104},
{"source":"CLEAVAGE","target":"NF2","value": 89},
{"source":"CLEAVAGE","target":"NON-NF2","value": 20},
{"source":"IMPAIR","target":"BIND","value": 42},
{"source":"IMPAIR","target":"INTERACT","value": 52},
{"source":"IMPAIR","target":"MERLIN","value": 94},
{"source":"IMPAIR","target":"NF2","value": 93},
{"source":"INTERACT","target":"BIND","value": 62},
{"source":"INTERACT","target":"IMPAIR","value": 52},
{"source":"INTERACT","target":"MERLIN","value": 114},
{"source":"INTERACT","target":"NF2","value": 113},
{"source":"MERLIN","target":"BIND","value": 104},
{"source":"MERLIN","target":"IMPAIR","value": 94},
{"source":"MERLIN","target":"INTERACT","value": 114},
{"source":"MERLIN","target":"NF2","value": 155},
{"source":"NF2","target":"CLEAVAGE","value": 89},
{"source":"NF2","target":"IMPAIR","value": 93},
{"source":"NF2","target":"INTERACT","value": 113},
{"source":"NF2","target":"MERLIN","value": 155},
{"source":"NF2","target":"NON-NF2","value": 85},
{"source":"NON-NF2","target":"CLEAVAGE","value": 20},
{"source":"NON-NF2","target":"NF2","value": 85},
{"source":"DOMINANT","target":"LOSS OF FUNCTION","value": 54},
{"source":"LOSS OF FUNCTION","target":"DOMINANT","value": 54},
{"source":"LOSS OF FUNCTION","target":"NF2","value": 101},
{"source":"NF2","target":"LOSS OF FUNCTION","value": 101},
{"source":"CONTROL","target":"MERLIN","value": 138},
{"source":"DOMINANT","target":"IMPROVE","value": 40},
{"source":"DOMINANT","target":"NEUROFIBROMATOSIS 2 (NF2) TUMOR SUPPRESSOR GENE","value": 32},
{"source":"IMPROVE","target":"DOMINANT","value": 40},
{"source":"IMPROVE","target":"NF2","value": 87},
{"source":"MERLIN","target":"CONTROL","value": 138},
{"source":"NEUROFIBROMATOSIS 2 (NF2) TUMOR SUPPRESSOR GENE","target":"DOMINANT","value": 32},
{"source":"NF2","target":"IMPROVE","value": 87},
{"source":"COMPETITIVE","target":"NF2","value": 87},
{"source":"CONTROL","target":"NF2","value": 137},
{"source":"NF2","target":"COMPETITIVE","value": 87},
{"source":"NF2","target":"CONTROL","value": 137},
{"source":"CLEAVAGE","target":"MERLIN","value": 90},
{"source":"COFACTOR","target":"MERLIN","value": 92},
{"source":"CONTROL","target":"DOMINANT","value": 90},
{"source":"CONTROL","target":"DROSOPHILA MERLIN","value": 66},
{"source":"CONTROL","target":"RESCUE","value": 72},
{"source":"CONTROL","target":"SCHWANNOMIN/MERLIN","value": 64},
{"source":"DOMINANT","target":"CONTROL","value": 90},
{"source":"DROSOPHILA MERLIN","target":"CONTROL","value": 66},
{"source":"DROSOPHILA MERLIN","target":"MERLIN","value": 84},
{"source":"DROSOPHILA MERLIN","target":"RESCUE","value": 18},
{"source":"MERLIN","target":"CLEAVAGE","value": 90},
{"source":"MERLIN","target":"COFACTOR","value": 92},
{"source":"MERLIN","target":"DROSOPHILA MERLIN","value": 84},
{"source":"MERLIN","target":"RESCUE","value": 90},
{"source":"MERLIN","target":"SUPPRESS","value": 114},
{"source":"NF2","target":"SCHWANNOMIN/MERLIN","value": 81},
{"source":"RESCUE","target":"CONTROL","value": 72},
{"source":"RESCUE","target":"DROSOPHILA MERLIN","value": 18},
{"source":"RESCUE","target":"MERLIN","value": 90},
{"source":"SCHWANNOMIN/MERLIN","target":"CONTROL","value": 64},
{"source":"SCHWANNOMIN/MERLIN","target":"NF2","value": 81},
{"source":"SUPPRESS","target":"MERLIN","value": 114},
{"source":"BIND","target":"COMPETITIVE","value": 36},
{"source":"COMPETITIVE","target":"BIND","value": 36},
{"source":"COMPETITIVE","target":"MERLIN","value": 88},
{"source":"CONTROL","target":"FRAMESHIFT","value": 68},
{"source":"FRAMESHIFT","target":"CONTROL","value": 68},
{"source":"FRAMESHIFT","target":"MERLIN","value": 86},
{"source":"MERLIN","target":"COMPETITIVE","value": 88},
{"source":"MERLIN","target":"FRAMESHIFT","value": 86},
{"source":"ENHANCE","target":"INTERACT","value": 54},
{"source":"ENHANCE","target":"LOSS OF FUNCTION","value": 42},
{"source":"ENHANCE","target":"MERLIN","value": 96},
{"source":"ENHANCE","target":"RECESSIVE","value": 30},
{"source":"IMPROVE","target":"INSERT","value": 14},
{"source":"INHIBIT","target":"INTERACT","value": 78},
{"source":"INHIBIT","target":"MERLIN","value": 120},
{"source":"INSERT","target":"IMPROVE","value": 14},
{"source":"INSERT","target":"NF2","value": 81},
{"source":"INTERACT","target":"ENHANCE","value": 54},
{"source":"INTERACT","target":"INHIBIT","value": 78},
{"source":"INTERACT","target":"LOSS OF FUNCTION","value": 60},
{"source":"INTERACT","target":"RECESSIVE","value": 48},
{"source":"LOSS OF FUNCTION","target":"ENHANCE","value": 42},
{"source":"LOSS OF FUNCTION","target":"INTERACT","value": 60},
{"source":"LOSS OF FUNCTION","target":"MERLIN","value": 102},
{"source":"LOSS OF FUNCTION","target":"RECESSIVE","value": 36},
{"source":"MERLIN","target":"ENHANCE","value": 96},
{"source":"MERLIN","target":"INHIBIT","value": 120},
{"source":"MERLIN","target":"LOSS OF FUNCTION","value": 102},
{"source":"MERLIN","target":"RECESSIVE","value": 90},
{"source":"NF2","target":"INSERT","value": 81},
{"source":"RECESSIVE","target":"ENHANCE","value": 30},
{"source":"RECESSIVE","target":"INTERACT","value": 48},
{"source":"RECESSIVE","target":"LOSS OF FUNCTION","value": 36},
{"source":"RECESSIVE","target":"MERLIN","value": 90},
{"source":"CLEAVAGE","target":"CONTROL","value": 72},
{"source":"CLEAVAGE","target":"IMPAIR","value": 28},
{"source":"CLEAVAGE","target":"INHIBITION","value": 60},
{"source":"CONTROL","target":"CLEAVAGE","value": 72},
{"source":"CONTROL","target":"IMPAIR","value": 76},
{"source":"IMPAIR","target":"CLEAVAGE","value": 28},
{"source":"IMPAIR","target":"CONTROL","value": 76},
{"source":"IMPAIR","target":"INHIBITION","value": 64},
{"source":"IMPAIR","target":"SUPPRESS","value": 52},
{"source":"INHIBITION","target":"CLEAVAGE","value": 60},
{"source":"INHIBITION","target":"IMPAIR","value": 64},
{"source":"INHIBITION","target":"MERLIN","value": 126},
{"source":"INHIBITION","target":"NF2","value": 125},
{"source":"MERLIN","target":"INHIBITION","value": 126},
{"source":"NF2","target":"INHIBITION","value": 125},
{"source":"NF2","target":"SUPPRESS","value": 113},
{"source":"SUPPRESS","target":"IMPAIR","value": 52},
{"source":"SUPPRESS","target":"NF2","value": 113},
{"source":"BLOCK","target":"MERLIN","value": 84},
{"source":"ERM/NF2","target":"SUPPRESS","value": 38},
{"source":"INHIBITION","target":"SUPPRESS","value": 84},
{"source":"MERLIN","target":"BLOCK","value": 84},
{"source":"SUPPRESS","target":"ERM/NF2","value": 38},
{"source":"SUPPRESS","target":"INHIBITION","value": 84},
{"source":"BLOCK","target":"C-TERMINAL DEFICIENT MERLIN MUTANT","value": 12},
{"source":"BLOCK","target":"SUPPRESS","value": 42},
{"source":"C-TERMINAL DEFICIENT MERLIN MUTANT","target":"BLOCK","value": 12},
{"source":"C-TERMINAL DEFICIENT MERLIN MUTANT","target":"MERLIN","value": 84},
{"source":"C-TERMINAL DEFICIENT MERLIN MUTANT","target":"SUPPRESS","value": 42},
{"source":"ENHANCE","target":"NF2","value": 95},
{"source":"INHIBIT","target":"NF2","value": 119},
{"source":"INTERACT","target":"REGULATION.NF2","value": 40},
{"source":"MERLIN","target":"C-TERMINAL DEFICIENT MERLIN MUTANT","value": 84},
{"source":"MERLIN","target":"REGULATION.NF2","value": 82},
{"source":"NF2","target":"ENHANCE","value": 95},
{"source":"NF2","target":"INHIBIT","value": 119},
{"source":"REGULATION.NF2","target":"INTERACT","value": 40},
{"source":"REGULATION.NF2","target":"MERLIN","value": 82},
{"source":"SUPPRESS","target":"BLOCK","value": 42},
{"source":"SUPPRESS","target":"C-TERMINAL DEFICIENT MERLIN MUTANT","value": 42},
{"source":"CONTROL","target":"ENHANCE","value": 78},
{"source":"ENHANCE","target":"CONTROL","value": 78},
{"source":"ENHANCE","target":"INHIBITION","value": 66},
{"source":"INHIBITION","target":"ENHANCE","value": 66},
{"source":"BIND","target":"INHIBIT","value": 68},
{"source":"CONTROL","target":"NON-NF2","value": 68},
{"source":"DOMINANT","target":"RECESSIVE","value": 42},
{"source":"INHIBIT","target":"BIND","value": 68},
{"source":"NON-NF2","target":"CONTROL","value": 68},
{"source":"RECESSIVE","target":"DOMINANT","value": 42},
{"source":"COFACTOR","target":"HIPPO","value": 66},
{"source":"COFACTOR","target":"WARTS/LATS","value": 20},
{"source":"CONTROL","target":"HIPPO","value": 112},
{"source":"CONTROL","target":"HIPPO","value": 112},
{"source":"CONTROL","target":"HIPPOCAMPAL","value": 64},
{"source":"CONTROL","target":"INTERACT","value": 96},
{"source":"DISRUPT","target":"INTERACT","value": 60},
{"source":"DISRUPT","target":"MERLIN","value": 102},
{"source":"DOMINANT","target":"OPERATION.NF2","value": 32},
{"source":"HIPPO","target":"COFACTOR","value": 66},
{"source":"HIPPO","target":"CONTROL","value": 112},
{"source":"HIPPO","target":"CONTROL","value": 112},
{"source":"HIPPO","target":"MERLIN","value": 130},
{"source":"HIPPO","target":"MERLIN","value": 130},
{"source":"HIPPO","target":"WARTS/LATS","value": 58},
{"source":"HIPPOCAMPAL","target":"CONTROL","value": 64},
{"source":"HIPPOCAMPAL","target":"MERLIN","value": 82},
{"source":"INTERACT","target":"CONTROL","value": 96},
{"source":"INTERACT","target":"DISRUPT","value": 60},
{"source":"MERLIN","target":"DISRUPT","value": 102},
{"source":"MERLIN","target":"HIPPO","value": 130},
{"source":"MERLIN","target":"HIPPO","value": 130},
{"source":"MERLIN","target":"HIPPOCAMPAL","value": 82},
{"source":"MERLIN","target":"WARTS/LATS","value": 84},
{"source":"OPERATION.NF2","target":"DOMINANT","value": 32},
{"source":"WARTS/LATS","target":"COFACTOR","value": 20},
{"source":"WARTS/LATS","target":"HIPPO","value": 58},
{"source":"WARTS/LATS","target":"MERLIN","value": 84},
{"source":"BENEFIT","target":"MERLIN","value": 94},
{"source":"BENEFIT","target":"NF2","value": 93},
{"source":"CONTROL","target":"YAP","value": 111},
{"source":"HIPPO","target":"INHIBITION","value": 100},
{"source":"HIPPO","target":"YAP","value": 103},
{"source":"IMPROVE","target":"INHIBITION","value": 58},
{"source":"IMPROVE","target":"MERLIN","value": 88},
{"source":"INHIBITION","target":"HIPPO","value": 100},
{"source":"INHIBITION","target":"IMPROVE","value": 58},
{"source":"INHIBITION","target":"YAP","value": 99},
{"source":"MERLIN","target":"BENEFIT","value": 94},
{"source":"MERLIN","target":"IMPROVE","value": 88},
{"source":"NF2","target":"BENEFIT","value": 93},
{"source":"YAP","target":"CONTROL","value": 111},
{"source":"YAP","target":"HIPPO","value": 103},
{"source":"YAP","target":"INHIBITION","value": 99},
{"source":"CONTROL","target":"WTS/LATS","value": 62},
{"source":"DOMINANT","target":"HIPPO","value": 82},
{"source":"DOMINANT","target":"INHIBIT","value": 72},
{"source":"HIPPO","target":"DOMINANT","value": 82},
{"source":"HIPPO","target":"INHIBIT","value": 94},
{"source":"HIPPO","target":"NF2","value": 129},
{"source":"INHIBIT","target":"DOMINANT","value": 72},
{"source":"INHIBIT","target":"HIPPO","value": 94},
{"source":"INHIBIT","target":"INHIBITION","value": 90},
{"source":"INHIBITION","target":"INHIBIT","value": 90},
{"source":"NF2","target":"HIPPO","value": 129},
{"source":"WTS/LATS","target":"CONTROL","value": 62},
{"source":"BIND","target":"ERBIN/MERLIN","value": 32},
{"source":"BIND","target":"INHIBITION","value": 74},
{"source":"ERBIN/MERLIN","target":"BIND","value": 32},
{"source":"ERBIN/MERLIN","target":"INHIBITION","value": 54},
{"source":"ERBIN/MERLIN","target":"MERLIN","value": 84},
{"source":"INHIBIT","target":"YKI/YAP","value": 44},
{"source":"INHIBITION","target":"BIND","value": 74},
{"source":"INHIBITION","target":"ERBIN/MERLIN","value": 54},
{"source":"MERLIN","target":"ERBIN/MERLIN","value": 84},
{"source":"YKI/YAP","target":"INHIBIT","value": 44},
{"source":"CONTROL","target":"HIPPO KINASE","value": 62},
{"source":"CONTROL","target":"SALVADOR-WARTS-HIPPO","value": 62},
{"source":"CRL4","target":"DISRUPT","value": 40},
{"source":"CRL4","target":"INHIBIT","value": 58},
{"source":"CRL4","target":"INTERACT","value": 52},
{"source":"CRL4","target":"MERLIN","value": 94},
{"source":"DISRUPT","target":"CRL4","value": 40},
{"source":"DISRUPT","target":"INHIBIT","value": 66},
{"source":"HIPPO","target":"LOSS OF FUNCTION","value": 76},
{"source":"HIPPO KINASE","target":"CONTROL","value": 62},
{"source":"INHIBIT","target":"CRL4","value": 58},
{"source":"INHIBIT","target":"DISRUPT","value": 66},
{"source":"INTERACT","target":"CRL4","value": 52},
{"source":"LOSS OF FUNCTION","target":"HIPPO","value": 76},
{"source":"MERLIN","target":"CRL4","value": 94},
{"source":"SALVADOR-WARTS-HIPPO","target":"CONTROL","value": 62},
{"source":"BENEFIT","target":"INHIBITION","value": 64},
{"source":"COMPETITIVE","target":"INHIBIT","value": 52},
{"source":"COMPETITIVE","target":"PATIENT-DERIVED MERLIN MUTANTS","value": 16},
{"source":"CRL4","target":"INHIBITION","value": 64},
{"source":"CRL4","target":"NF2","value": 93},
{"source":"CRL4","target":"SUPPRESS","value": 52},
{"source":"CRL4","target":"UBIQUITIN","value": 32},
{"source":"DISRUPT","target":"HIPPO","value": 76},
{"source":"DISRUPT","target":"INHIBITION","value": 72},
{"source":"DISRUPT","target":"NF2","value": 101},
{"source":"DISRUPT","target":"SUPPRESS","value": 60},
{"source":"DISRUPT","target":"UBIQUITIN","value": 40},
{"source":"HIPPO","target":"DISRUPT","value": 76},
{"source":"INHIBIT","target":"COMPETITIVE","value": 52},
{"source":"INHIBIT","target":"PATIENT-DERIVED MERLIN MUTANTS","value": 48},
{"source":"INHIBIT","target":"UBIQUITIN","value": 58},
{"source":"INHIBITION","target":"BENEFIT","value": 64},
{"source":"INHIBITION","target":"CRL4","value": 64},
{"source":"INHIBITION","target":"DISRUPT","value": 72},
{"source":"INHIBITION","target":"INTERACT","value": 84},
{"source":"INHIBITION","target":"UBIQUITIN","value": 64},
{"source":"INTERACT","target":"INHIBITION","value": 84},
{"source":"INTERACT","target":"SUPPRESS","value": 72},
{"source":"INTERACT","target":"UBIQUITIN","value": 52},
{"source":"MERLIN","target":"PATIENT-DERIVED MERLIN MUTANTS","value": 84},
{"source":"MERLIN","target":"UBIQUITIN","value": 94},
{"source":"NF2","target":"CRL4","value": 93},
{"source":"NF2","target":"DISRUPT","value": 101},
{"source":"NF2","target":"UBIQUITIN","value": 93},
{"source":"PATIENT-DERIVED MERLIN MUTANTS","target":"COMPETITIVE","value": 16},
{"source":"PATIENT-DERIVED MERLIN MUTANTS","target":"INHIBIT","value": 48},
{"source":"PATIENT-DERIVED MERLIN MUTANTS","target":"MERLIN","value": 84},
{"source":"SUPPRESS","target":"CRL4","value": 52},
{"source":"SUPPRESS","target":"DISRUPT","value": 60},
{"source":"SUPPRESS","target":"INTERACT","value": 72},
{"source":"SUPPRESS","target":"UBIQUITIN","value": 52},
{"source":"UBIQUITIN","target":"CRL4","value": 32},
{"source":"UBIQUITIN","target":"DISRUPT","value": 40},
{"source":"UBIQUITIN","target":"INHIBIT","value": 58},
{"source":"UBIQUITIN","target":"INHIBITION","value": 64},
{"source":"UBIQUITIN","target":"INTERACT","value": 52},
{"source":"UBIQUITIN","target":"MERLIN","value": 94},
{"source":"UBIQUITIN","target":"NF2","value": 93},
{"source":"UBIQUITIN","target":"SUPPRESS","value": 52},
{"source":"BIND","target":"LOSS OF FUNCTION","value": 50},
{"source":"CHAPERONE","target":"MERLIN","value": 80},
{"source":"ENHANCE","target":"HIPPO","value": 70},
{"source":"ENHANCE","target":"YAP","value": 69},
{"source":"HIPPO","target":"ENHANCE","value": 70},
{"source":"HIPPO","target":"SUPPRESS","value": 88},
{"source":"HIPPO","target":"YAP1","value": 71},
{"source":"INHIBITION","target":"LOSS OF FUNCTION","value": 72},
{"source":"INHIBITION","target":"YAP1","value": 67},
{"source":"LOSS OF FUNCTION","target":"BIND","value": 50},
{"source":"LOSS OF FUNCTION","target":"INHIBITION","value": 72},
{"source":"MERLIN","target":"CHAPERONE","value": 80},
{"source":"MERLIN","target":"YAP","value": 129},
{"source":"NF2","target":"YAP","value": 128},
{"source":"SUPPRESS","target":"HIPPO","value": 88},
{"source":"SUPPRESS","target":"YAP1","value": 55},
{"source":"YAP","target":"ENHANCE","value": 69},
{"source":"YAP","target":"MERLIN","value": 129},
{"source":"YAP","target":"NF2","value": 128},
{"source":"YAP1","target":"HIPPO","value": 71},
{"source":"YAP1","target":"INHIBITION","value": 67},
{"source":"YAP1","target":"SUPPRESS","value": 55},
{"source":"COFACTOR","target":"INHIBIT","value": 56},
{"source":"COFACTOR","target":"INTERACT","value": 50},
{"source":"COFACTOR","target":"TUMOR SUPPRESSOR MERLIN","value": 18},
{"source":"COFACTOR","target":"YAP","value": 65},
{"source":"CONTROL","target":"SALVADOR/WARTS/HIPPO","value": 66},
{"source":"HIPPO","target":"INTERACT","value": 88},
{"source":"HIPPO","target":"SALVADOR/WARTS/HIPPO","value": 58},
{"source":"INHIBIT","target":"COFACTOR","value": 56},
{"source":"INHIBIT","target":"YAP","value": 93},
{"source":"INHIBITION","target":"SALVADOR/WARTS/HIPPO","value": 54},
{"source":"INTERACT","target":"COFACTOR","value": 50},
{"source":"INTERACT","target":"HIPPO","value": 88},
{"source":"INTERACT","target":"YAP","value": 87},
{"source":"LATS-YAP","target":"SUPPRESS","value": 40},
{"source":"LATS-YAP","target":"YAP","value": 55},
{"source":"SALVADOR/WARTS/HIPPO","target":"CONTROL","value": 66},
{"source":"SALVADOR/WARTS/HIPPO","target":"HIPPO","value": 58},
{"source":"SALVADOR/WARTS/HIPPO","target":"INHIBITION","value": 54},
{"source":"SUPPRESS","target":"LATS-YAP","value": 40},
{"source":"SUPPRESS","target":"YAP","value": 87},
{"source":"TUMOR SUPPRESSOR MERLIN","target":"COFACTOR","value": 18},
{"source":"TUMOR SUPPRESSOR MERLIN","target":"YAP","value": 55},
{"source":"YAP","target":"COFACTOR","value": 65},
{"source":"YAP","target":"INHIBIT","value": 93},
{"source":"YAP","target":"INTERACT","value": 87},
{"source":"YAP","target":"LATS-YAP","value": 55},
{"source":"YAP","target":"SUPPRESS","value": 87},
{"source":"YAP","target":"TUMOR SUPPRESSOR MERLIN","value": 55},
{"source":"YAP","target":"YAP","value": 102},
{"source":"CONTROL","target":"HOUSE-BRACKMANNNF2","value": 64},
{"source":"CONTROL","target":"NEUROFIBROMATOSIS 2 (NF2) GENE","value": 64},
{"source":"DISRUPT","target":"YAP","value": 75},
{"source":"HOUSE-BRACKMANNNF2","target":"CONTROL","value": 64},
{"source":"HOUSE-BRACKMANNNF2","target":"NF2","value": 81},
{"source":"MERLIN","target":"NEUROFIBROMATOSIS 2 (NF2) GENE","value": 82},
{"source":"NEUROFIBROMATOSIS 2 (NF2) GENE","target":"CONTROL","value": 64},
{"source":"NEUROFIBROMATOSIS 2 (NF2) GENE","target":"MERLIN","value": 82},
{"source":"NF2","target":"HOUSE-BRACKMANNNF2","value": 81},
{"source":"NF2","target":"RESCUE","value": 89},
{"source":"RESCUE","target":"NF2","value": 89},
{"source":"YAP","target":"DISRUPT","value": 75},
{"source":"BIND","target":"DOMINANT","value": 56},
{"source":"BIND","target":"Δ2-4)MERLIN","value": 30},
{"source":"CONTROL","target":"INHIBIT","value": 102},
{"source":"CONTROL","target":"NON-NF2 POPULATION","value": 66},
{"source":"CONTROL","target":"YAP","value": 111},
{"source":"DOMINANT","target":"BIND","value": 56},
{"source":"DOMINANT","target":"NON-NF2 POPULATION","value": 36},
{"source":"DOMINANT","target":"TUMOUR SUPPRESSOR MERLIN","value": 34},
{"source":"INHIBIT","target":"CONTROL","value": 102},
{"source":"INHIBIT","target":"YAP","value": 93},
{"source":"LATS1-PSEN1","target":"SUPPRESS","value": 38},
{"source":"MERLIN","target":"Δ2-4)MERLIN","value": 82},
{"source":"NF2","target":"NON-NF2 POPULATION","value": 83},
{"source":"NF2","target":"TUMOUR SUPPRESSOR MERLIN","value": 81},
{"source":"NON-NF2 POPULATION","target":"CONTROL","value": 66},
{"source":"NON-NF2 POPULATION","target":"DOMINANT","value": 36},
{"source":"NON-NF2 POPULATION","target":"NF2","value": 83},
{"source":"SUPPRESS","target":"LATS1-PSEN1","value": 38},
{"source":"TUMOUR SUPPRESSOR MERLIN","target":"DOMINANT","value": 34},
{"source":"TUMOUR SUPPRESSOR MERLIN","target":"NF2","value": 81},
{"source":"YAP","target":"CONTROL","value": 111},
{"source":"YAP","target":"INHIBIT","value": 93},
{"source":"Δ2-4)MERLIN","target":"BIND","value": 30},
{"source":"Δ2-4)MERLIN","target":"MERLIN","value": 82},
{"source":"BENEFIT","target":"LOSS OF FUNCTION","value": 40},
{"source":"BENEFIT","target":"MELANOMA),NF2(IE","value": 24},
{"source":"BENEFIT","target":"NF2","value": 93},
{"source":"BENEFIT","target":"NON-NF2","value": 24},
{"source":"BIND","target":"YAP1","value": 45},
{"source":"CONTROL","target":"DISRUPT","value": 84},
{"source":"CONTROL","target":"HIPPO","value": 112},
{"source":"CONTROL","target":"YAP","value": 111},
{"source":"CONTROL","target":"YAP1","value": 79},
{"source":"DISRUPT","target":"CONTROL","value": 84},
{"source":"DISRUPT","target":"YAP","value": 75},
{"source":"DOMINANT","target":"NF2","value": 107},
{"source":"HIPPO","target":"CONTROL","value": 112},
{"source":"HIPPO","target":"INHIBIT","value": 94},
{"source":"HIPPO","target":"INHIBITION","value": 100},
{"source":"HIPPO","target":"REPRESS","value": 58},
{"source":"HIPPO","target":"YAP","value": 103},
{"source":"HIPPO","target":"YAP","value": 103},
{"source":"HIPPO","target":"YAP","value": 103},
{"source":"HIPPO","target":"YAP1","value": 71},
{"source":"INHIBIT","target":"HIPPO","value": 94},
{"source":"INHIBIT","target":"YAP","value": 93},
{"source":"INHIBIT","target":"YAP1","value": 61},
{"source":"INHIBITION","target":"HIPPO","value": 100},
{"source":"INHIBITION","target":"RESCUE","value": 60},
{"source":"INHIBITION","target":"YAP","value": 99},
{"source":"LOSS OF FUNCTION","target":"BENEFIT","value": 40},
{"source":"LOSS OF FUNCTION","target":"MELANOMA),NF2(IE","value": 32},
{"source":"LOSS OF FUNCTION","target":"NF2","value": 101},
{"source":"MELANOMA),NF2(IE","target":"BENEFIT","value": 24},
{"source":"MELANOMA),NF2(IE","target":"LOSS OF FUNCTION","value": 32},
{"source":"MELANOMA),NF2(IE","target":"MERLIN","value": 86},
{"source":"MELANOMA),NF2(IE","target":"NF2","value": 85},
{"source":"MERLIN","target":"MELANOMA),NF2(IE","value": 86},
{"source":"MERLIN","target":"NF2","value": 155},
{"source":"MERLIN","target":"YAP1","value": 97},
{"source":"NF2","target":"BENEFIT","value": 93},
{"source":"NF2","target":"DOMINANT","value": 107},
{"source":"NF2","target":"LOSS OF FUNCTION","value": 101},
{"source":"NF2","target":"MELANOMA),NF2(IE","value": 85},
{"source":"NF2","target":"MERLIN","value": 155},
{"source":"NF2","target":"NF2","value": 154},
{"source":"NF2","target":"REPRESS","value": 83},
{"source":"NF2","target":"YAP","value": 128},
{"source":"NF2","target":"YAP1","value": 96},
{"source":"NON-NF2","target":"BENEFIT","value": 24},
{"source":"REPRESS","target":"HIPPO","value": 58},
{"source":"REPRESS","target":"NF2","value": 83},
{"source":"REPRESS","target":"YAP","value": 57},
{"source":"RESCUE","target":"INHIBITION","value": 60},
{"source":"RESCUE","target":"SUPPRESS","value": 48},
{"source":"SUPPRESS","target":"RESCUE","value": 48},
{"source":"YAP","target":"CONTROL","value": 111},
{"source":"YAP","target":"DISRUPT","value": 75},
{"source":"YAP","target":"HIPPO","value": 103},
{"source":"YAP","target":"HIPPO","value": 103},
{"source":"YAP","target":"HIPPO","value": 103},
{"source":"YAP","target":"INHIBIT","value": 93},
{"source":"YAP","target":"INHIBITION","value": 99},
{"source":"YAP","target":"NF2","value": 128},
{"source":"YAP","target":"REPRESS","value": 57},
{"source":"YAP","target":"YAP","value": 102},
{"source":"YAP","target":"YAP","value": 102},
{"source":"YAP1","target":"BIND","value": 45},
{"source":"YAP1","target":"CONTROL","value": 79},
{"source":"YAP1","target":"HIPPO","value": 71},
{"source":"YAP1","target":"INHIBIT","value": 61},
{"source":"YAP1","target":"MERLIN","value": 97},
{"source":"YAP1","target":"NF2","value": 96},
{"source":"YAP1","target":"YAP1","value": 38},
{"source":"BENEFIT","target":"SUPPRESSION.NF2","value": 18},
{"source":"SUPPRESSION.NF2","target":"BENEFIT","value": 18},
{"source":"DOMINANT","target":"FRAMESHIFT","value": 38},
{"source":"FRAMESHIFT","target":"DOMINANT","value": 38},
{"source":"FRAMESHIFT","target":"NF2","value": 85},
{"source":"INHIBIT","target":"SUPPRESS","value": 78},
{"source":"NF2","target":"FRAMESHIFT","value": 85},
{"source":"SUPPRESS","target":"INHIBIT","value": 78}
]}