This is a little Gist I made to help others looking into buying a Framework mainboard for a homelab / NAS purpose. It's a mix of research I have undertaken to look for parts to work around the limited expansion capabilities of the Framework Desktop mainboard.
Bear in mind, this guide does not cheap out! It ensures that you get the best performance and reliability for your homelab or NAS setup for personal use only and maximises the potential of the Framework Desktop mainboard given its limitations. You may need to expand on my research to find the best components for your specific use case if your budget is more limiting.
While the Framework desktop mainboard is a beast in terms of its compute performance, and up to 128GB of unified memory, it only has two M.2 slots for storage expansion. This can be a limiting factor for users looking to build a high-capacity NAS or homelab environment.