A minimal script to get started with using ComfyUI as a library

comfyui_headless.py

import sys, os

comfy_path = "/content/ComfyUI"
sys.path.insert(0, comfy_path)

import importlib.util

utils_path = os.path.join(comfy_path, "utils")
spec = importlib.util.spec_from_file_location("utils", os.path.join(utils_path, "__init__.py") if os.path.exists(os.path.join(utils_path, "__init__.py")) else os.devnull)
utils = importlib.util.module_from_spec(spec)
sys.modules["utils"] = utils

import nodes
import asyncio

from server import PromptServer

loop = asyncio.new_event_loop()
PromptServer.instance = PromptServer(loop)

async def t():
    await nodes.init_external_custom_nodes()
    n = nodes.NODE_CLASS_MAPPINGS
    for item in n:
        if item.find("VHS_") != -1:
            print(item)

asyncio.run(t())

For example, for Wan 2.1 T2V with lightx2v LoRA:

download_file("Comfy-Org/Wan_2.1_ComfyUI_repackaged", "split_files/vae/wan_2.1_vae.safetensors", "vae")
download_file("city96/Wan2.1-T2V-14B-gguf", "wan2.1-t2v-14b-Q4_K_M.gguf", "unet")
download_file("Comfy-Org/Wan_2.1_ComfyUI_repackaged", "split_files/text_encoders/umt5_xxl_fp8_e4m3fn_scaled.safetensors", "text_encoders")
download_file("lightx2v/Wan2.1-T2V-14B-StepDistill-CfgDistill-Lightx2v", "loras/Wan21_T2V_14B_lightx2v_cfg_step_distill_lora_rank64.safetensors", "loras")