Pyside example of dragging and dropping a file onto a GUI. See http://www.birving.com/blog/2015/09/29/drag-and-drop-files-into-gui-using/

pyside_drag_drop_image_file.py

"""

A simple example pyside app that demonstrates dragging and dropping
of files onto a GUI. 

- This app allows dragging and dropping of an image file 
that this then displayed in the GUI
- Alternatively an image can be loaded using the button
- This app includes a workaround for using pyside for dragging and dropping
with OSx
- This app should work on Linux, Windows and OSx

"""

from __future__ import division, unicode_literals, print_function, absolute_import

from PySide import QtGui, QtCore
import sys
import platform

# Use NSURL as a workaround to pyside/Qt4 behaviour for dragging and dropping on OSx
op_sys = platform.system()
if op_sys == 'Darwin':
    from Foundation import NSURL


class MainWindowWidget(QtGui.QWidget):
    """
    Subclass the widget and add a button to load images. 
    
    Alternatively set up dragging and dropping of image files onto the widget
    """

    def __init__(self):
        super(MainWindowWidget, self).__init__()

        # Button that allows loading of images
        self.load_button = QtGui.QPushButton("Load image")
        self.load_button.clicked.connect(self.load_image_but)

        # Image viewing region
        self.lbl = QtGui.QLabel(self)

        # A horizontal layout to include the button on the left
        layout_button = QtGui.QHBoxLayout()
        layout_button.addWidget(self.load_button)
        layout_button.addStretch()

        # A Vertical layout to include the button layout and then the image
        layout = QtGui.QVBoxLayout()
        layout.addLayout(layout_button)
        layout.addWidget(self.lbl)

        self.setLayout(layout)

        # Enable dragging and dropping onto the GUI
        self.setAcceptDrops(True)

        self.show()

    def load_image_but(self):
        """
        Open a File dialog when the button is pressed

        :return:
        """
        
        #Get the file location
        self.fname, _ = QtGui.QFileDialog.getOpenFileName(self, 'Open file')
        # Load the image from the location
        self.load_image()

    def load_image(self):
        """
        Set the image to the pixmap

        :return:
        """
        pixmap = QtGui.QPixmap(self.fname)
        pixmap = pixmap.scaled(500, 500, QtCore.Qt.KeepAspectRatio)
        self.lbl.setPixmap(pixmap)

    # The following three methods set up dragging and dropping for the app
    def dragEnterEvent(self, e):
        if e.mimeData().hasUrls:
            e.accept()
        else:
            e.ignore()

    def dragMoveEvent(self, e):
        if e.mimeData().hasUrls:
            e.accept()
        else:
            e.ignore()

    def dropEvent(self, e):
        """
        Drop files directly onto the widget

        File locations are stored in fname
        :param e:
        :return:
        """
        if e.mimeData().hasUrls:
            e.setDropAction(QtCore.Qt.CopyAction)
            e.accept()
            # Workaround for OSx dragging and dropping
            for url in e.mimeData().urls():
                if op_sys == 'Darwin':
                    fname = str(NSURL.URLWithString_(str(url.toString())).filePathURL().path())
                else:
                    fname = str(url.toLocalFile())

            self.fname = fname
            self.load_image()
        else:
            e.ignore()

# Run if called directly
if __name__ == '__main__':
    # Initialise the application
    app = QtGui.QApplication(sys.argv)
    # Call the widget
    ex = MainWindowWidget()
    sys.exit(app.exec_())

Great example. Easy to follow and understand what's happening. Helped me a ton. Thanks a bunch.

Is there an updated version for python 3?

Is there an updated version for python 3?

Good point @TyLaneTech. This needs an update.